Mastocarcinoma therapy synergistically promoted by lysosome dependent apoptosis specifically evoked by 5-Fu@nanogel system with passive targeting and pH activatable dual function. [electronic resource]
Producer: 20181002Description: 107-118 p. digitalISSN:- 1873-4995
- Animals
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- Breast Neoplasms -- drug therapy
- Caspase 9 -- metabolism
- Cathepsin B -- metabolism
- Cell Line, Tumor
- Cell Membrane Permeability
- Cytochromes c -- metabolism
- Drug Carriers
- Female
- Fluorouracil -- administration & dosage
- Gels
- Humans
- Hydrogen-Ion Concentration
- Imines -- chemistry
- Lysosomes -- metabolism
- Membrane Potential, Mitochondrial
- Mice, Inbred BALB C
- Mice, Nude
- Mitochondria -- drug effects
- Molecular Targeted Therapy
- Nanostructures -- chemistry
- Particle Size
- Polyethylenes -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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