A newly identified amino acid substitution T123I in the 14α-demethylase (Erg11p) of Candida albicans confers azole resistance. [electronic resource]
Producer: 20180515ISSN:- 1567-1364
- Amino Acid Substitution
- Antifungal Agents -- chemistry
- Binding Sites
- Candida albicans -- drug effects
- Cytochrome P-450 Enzyme System -- chemistry
- Drug Resistance, Fungal -- genetics
- Fluconazole -- chemistry
- Fungal Proteins -- chemistry
- Gene Expression Regulation, Fungal
- Isoleucine -- chemistry
- Itraconazole -- chemistry
- Microbial Sensitivity Tests
- Models, Molecular
- Open Reading Frames
- Phosphorylation
- Protein Binding
- Protein Conformation, alpha-Helical
- Protein Interaction Domains and Motifs
- Saccharomyces cerevisiae -- drug effects
- Threonine -- chemistry
- Voriconazole -- chemistry
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Publication Type: Journal Article
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