Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R). [electronic resource]
Producer: 20170710Description: 7131-7144 p. digitalISSN:- 1083-351X
- Azides -- chemistry
- Binding Sites
- Cyclic AMP -- metabolism
- Diabetes Mellitus, Type 2 -- metabolism
- Exenatide
- Glucagon-Like Peptide-1 Receptor -- chemistry
- HEK293 Cells
- Humans
- Ligands
- Molecular Dynamics Simulation
- Molecular Structure
- Mutagenesis
- Mutation
- Peptides -- chemistry
- Phenylalanine -- analogs & derivatives
- Protein Domains
- Protein Multimerization
- Structure-Activity Relationship
- Ultraviolet Rays
- Venoms -- chemistry
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Publication Type: Journal Article
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