AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction. [electronic resource]
Producer: 20170428Description: 995-1010 p. digitalISSN:- 1460-2075
- Animals
- Bridged-Ring Compounds -- pharmacology
- Cell Line, Tumor
- Drug Resistance, Neoplasm
- Forkhead Box Protein O1 -- genetics
- Humans
- MAP Kinase Signaling System
- Male
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Mitogen-Activated Protein Kinase 1 -- genetics
- Mitogen-Activated Protein Kinase 3 -- genetics
- Phosphatidylinositol 3-Kinases -- genetics
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation -- genetics
- Prostatic Neoplasms -- genetics
- Proto-Oncogene Proteins c-akt -- genetics
- Taxoids -- pharmacology
- Xenograft Model Antitumor Assays
- ras GTPase-Activating Proteins -- genetics
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Publication Type: Journal Article
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