MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation. [electronic resource]
Producer: 20181114Description: 14674 p. digitalISSN:- 2041-1723
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors -- genetics
- Cell Cycle -- genetics
- Cell Proliferation -- genetics
- Chromosome Deletion
- Chromosomes, Human, Pair 14 -- genetics
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- DNA Mutational Analysis
- Disease Progression
- Female
- Gastrointestinal Neoplasms -- genetics
- Gastrointestinal Stromal Tumors -- genetics
- Gene Silencing
- Humans
- Loss of Function Mutation
- Male
- Neurofibromin 1 -- genetics
- Proto-Oncogene Proteins c-kit -- genetics
- Receptor, Platelet-Derived Growth Factor alpha -- genetics
- Succinate Dehydrogenase -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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