Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120. [electronic resource]
Producer: 20170424Description: 3124-3153 p. digitalISSN:- 1520-4804
- Anti-HIV Agents -- chemistry
- Biomimetic Materials -- chemistry
- CD4 Antigens -- chemistry
- Cell Line
- Crystallography, X-Ray
- HIV Envelope Protein gp120 -- chemistry
- HIV Infections -- drug therapy
- HIV-1 -- drug effects
- Humans
- Molecular Docking Simulation
- Molecular Targeted Therapy
- Pyrroles -- chemistry
- Structure-Activity Relationship
- Thiazoles -- chemistry
- Virus Internalization -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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