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Details for: A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies.

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A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies. [electronic resource]

By:

Cukierman, Daphne Schneider

Contributor(s):

Pinheiro, Ana Beatriz
Castiñeiras-Filho, Sergio L P
da Silva, Anastácia Sá P
Miotto, Marco C
De Falco, Anna
de P Ribeiro, Thales
Maisonette, Silvia
da Cunha, Alessandra L M C
Hauser-Davis, Rachel A
Landeira-Fernandez, J
Aucélio, Ricardo Q
Outeiro, Tiago F
Pereira, Marcos D
Fernández, Claudio O
Rey, Nicolás A

Producer: 20170918Description: 160-168 p. digitalISSN:

1873-3344

Subject(s):

Animals
Blood-Brain Barrier -- metabolism
Chelating Agents -- chemical synthesis
Drug Evaluation, Preclinical
Hydrazones -- chemical synthesis
Male
Parkinson Disease, Secondary -- drug therapy
Rats
Rats, Wistar

Online resources:

Available from publisher's website

In: Journal of inorganic biochemistry vol. 170

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Publication Type: Journal Article; Research Support, Non-U.S. Gov't

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1 Beta-adrenergic agonist-induced long-lasting synaptic modifications in hippocampal dentate gyrus require activation of NMDA receptors, but not electrical activation of afferents.
by Dahl, D
2 Norepinephrine induces pathway-specific long-lasting potentiation and depression in the hippocampal dentate gyrus.
by Dahl, D
3 Blockade of long-term potentiation in rat hippocampal CA1 region by inhibitors of protein synthesis.
by Stanton, P K
4 Long-lasting potentiation and epileptiform activity produced by GABAB receptor activation in the dentate gyrus of rat hippocampal slice.
by Burgard, E C
5 gamma-Aminobutyrate sensitivity does not change during long-term potentiation in rat hippocampal slices.
by Scharfman, H E
6 Physiological correlates of responses to gamma-aminobutyric acid (GABA) recorded from rat visual cortical neurons in vitro.
by Scharfman, H E
7 Responses to GABA recorded from identified rat visual cortical neurons.
by Scharfman, H E
8 Norepinephrine regulates long-term potentiation of both the population spike and dendritic EPSP in hippocampal dentate gyrus.
by Stanton, P K
9 Connectivity of the hilar region of the hippocampal formation in the rat.
by Schwerdtfeger, W K
10 Effects of cholinesterase inhibitors on evoked responses in field CA1 of the rat hippocampus.
by Williamson, A M
11 Blockade of norepinephrine-induced long-lasting potentiation in the hippocampal dentate gyrus by an inhibitor of protein synthesis.
by Stanton, P K
12 Endogenous activation of mu and delta-1 opioid receptors is required for long-term potentiation induction in the lateral perforant path: dependence on GABAergic inhibition.
by Bramham, C R
13 Postsynaptic firing during repetitive stimulation is required for long-term potentiation in hippocampus.
by Scharfman, H E
14 The effect of high-frequency electrical stimulation and norepinephrine on cyclic AMP levels in normal versus norepinephrine-depleted rat hippocampal slices.
by Stanton, P K
15 Depletion of norepinephrine, but not serotonin, reduces long-term potentiation in the dentate gyrus of rat hippocampal slices.
by Stanton, P K
16 Muscarinic receptor activation facilitates the induction of long-term potentiation (LTP) in the rat dentate gyrus.
by Burgard, E C
17 Responses to gamma-aminobutyric acid applied to cell bodies and dendrites of rat visual cortical neurons.
by Scharfman, H E
18 Lowering extracellular calcium reverses paired pulse habituation into facilitation in dentate granule cells and removes a late IPSP.
by Rausche, G
19 Slow synaptic inhibition in relation to frequency habituation in dentate granule cells of rat hippocampal slices.
by Rausche, G
20 NMDA receptor antagonists reduce medial, but not lateral, perforant path-evoked EPSPs in dentate gyrus of rat hippocampal slice.
by Dahl, D

A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies.

APA

Cukierman D. S., Pinheiro A. B., Castiñeiras-Filho S. L. P., da Silva A. S. P., Miotto M. C., De Falco A., de P Ribeiro T., Maisonette S., da Cunha A. L. M. C., Hauser-Davis R. A., Landeira-Fernandez J., Aucélio R. Q., Outeiro T. F., Pereira M. D., Fernández C. O. & Rey N. A. (20170918). A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies. : Journal of inorganic biochemistry.

Chicago

Cukierman Daphne Schneider, Pinheiro Ana Beatriz, Castiñeiras-Filho Sergio L P, da Silva Anastácia Sá P, Miotto Marco C, De Falco Anna, de P Ribeiro Thales, Maisonette Silvia, da Cunha Alessandra L M C, Hauser-Davis Rachel A, Landeira-Fernandez J, Aucélio Ricardo Q, Outeiro Tiago F, Pereira Marcos D, Fernández Claudio O and Rey Nicolás A. 20170918. A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies. : Journal of inorganic biochemistry.

Harvard

Cukierman D. S., Pinheiro A. B., Castiñeiras-Filho S. L. P., da Silva A. S. P., Miotto M. C., De Falco A., de P Ribeiro T., Maisonette S., da Cunha A. L. M. C., Hauser-Davis R. A., Landeira-Fernandez J., Aucélio R. Q., Outeiro T. F., Pereira M. D., Fernández C. O. and Rey N. A. (20170918). A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies. : Journal of inorganic biochemistry.

MLA

Cukierman Daphne Schneider, Pinheiro Ana Beatriz, Castiñeiras-Filho Sergio L P, da Silva Anastácia Sá P, Miotto Marco C, De Falco Anna, de P Ribeiro Thales, Maisonette Silvia, da Cunha Alessandra L M C, Hauser-Davis Rachel A, Landeira-Fernandez J, Aucélio Ricardo Q, Outeiro Tiago F, Pereira Marcos D, Fernández Claudio O and Rey Nicolás A. A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies. : Journal of inorganic biochemistry. 20170918.

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