Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function. [electronic resource]
Producer: 20170613Description: 224-231 p. digitalISSN:- 1090-2104
- AMP-Activated Protein Kinases -- genetics
- Adenosine Triphosphate -- metabolism
- Amino Acids, Branched-Chain -- metabolism
- Breast Neoplasms -- genetics
- Carcinoma -- genetics
- Cell Line, Tumor
- Cell Proliferation
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- MCF-7 Cells
- Mitochondria -- metabolism
- Organelle Biogenesis
- RNA, Small Interfering -- genetics
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- Sirtuin 1 -- genetics
- TOR Serine-Threonine Kinases -- genetics
- Transaminases -- antagonists & inhibitors
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Publication Type: Journal Article
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