Berberine improves cognitive impairment by promoting autophagic clearance and inhibiting production of β-amyloid in APP/tau/PS1 mouse model of Alzheimer's disease. [electronic resource]
Producer: 20171026Description: 25-33 p. digitalISSN:- 1873-6815
- Alzheimer Disease -- drug therapy
- Amyloid Precursor Protein Secretases -- metabolism
- Amyloid beta-Peptides -- metabolism
- Animals
- Aspartic Acid Endopeptidases -- metabolism
- Autophagy -- drug effects
- Berberine -- pharmacology
- Brain -- pathology
- Cognitive Dysfunction -- drug therapy
- Female
- Humans
- Male
- Maze Learning -- drug effects
- Memory -- drug effects
- Mice
- Mice, Transgenic
- Neurons -- metabolism
- Neuroprotective Agents -- pharmacology
- Plaque, Amyloid -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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