Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release. [electronic resource]
Producer: 20180426Description: 247-257 p. digitalISSN:- 1873-4596
- Animals
- Antioxidants -- therapeutic use
- Beer
- Carotid Arteries -- drug effects
- Cell Adhesion Molecules -- metabolism
- Chlorides -- administration & dosage
- DNA, Mitochondrial -- genetics
- Dendritic Cells -- physiology
- Ferric Compounds -- administration & dosage
- Fibrinolytic Agents -- therapeutic use
- Flavonoids -- metabolism
- Hemorrhage
- Humans
- Humulus -- metabolism
- Lectins, C-Type -- metabolism
- Mice
- Mice, Inbred C57BL
- Platelet Activation
- Platelet Aggregation Inhibitors -- therapeutic use
- Propiophenones -- metabolism
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Receptors, Cell Surface -- metabolism
- Risk
- Sirtuin 1 -- metabolism
- Thrombosis -- prevention & control
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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