Expanded safety analysis of pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukemia and myelodysplastic syndromes. [electronic resource]
Producer: 20180827Description: e520 p. digitalISSN:- 2044-5385
- Adult
- Aged
- Aged, 80 and over
- Cyclopentanes -- administration & dosage
- Enzyme Inhibitors -- administration & dosage
- Female
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Male
- Maximum Tolerated Dose
- Middle Aged
- Myelodysplastic Syndromes -- drug therapy
- NEDD8 Protein -- antagonists & inhibitors
- Pyrimidines -- administration & dosage
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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