Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice. [electronic resource]
Producer: 20170808Description: 1419-1433.e5 p. digitalISSN:- 1528-0012
- AMP-Activated Protein Kinases -- genetics
- Acetophenones -- pharmacology
- Adenoma -- metabolism
- Aged
- Animals
- Azoxymethane
- Biopsy
- Biosynthetic Pathways -- genetics
- Caco-2 Cells
- Case-Control Studies
- Cell Proliferation
- Cholesterol -- biosynthesis
- Colon -- microbiology
- Colonic Neoplasms -- chemically induced
- DNA, Bacterial -- analysis
- Enzyme Inhibitors -- pharmacology
- Feces -- microbiology
- Gene Expression
- Gram-Positive Bacterial Infections -- complications
- HT29 Cells
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Middle Aged
- Peptostreptococcus -- isolation & purification
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- genetics
- Sterol Regulatory Element Binding Protein 2 -- metabolism
- Toll-Like Receptor 2 -- genetics
- Toll-Like Receptor 4 -- genetics
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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