Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway. [electronic resource]
Producer: 20181119Description: 13700 p. digitalISSN:- 2041-1723
- ADP Ribose Transferases
- Animals
- Bone Density
- Botulinum Toxins
- Female
- GTP-Binding Protein alpha Subunits, G12-G13 -- genetics
- Gene Expression Regulation -- drug effects
- Gene Silencing
- Glycogen Synthase Kinase 3 beta -- genetics
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Humans
- Leukocytes, Mononuclear -- physiology
- Lipoproteins -- toxicity
- Macrophage Colony-Stimulating Factor
- Male
- Mice
- NFATC Transcription Factors -- genetics
- Osteogenesis -- physiology
- Ovariectomy
- Proto-Oncogene Proteins c-akt -- genetics
- RANK Ligand
- Signal Transduction -- physiology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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