Pharmacokinetic/Pharmacodynamic Modeling of the PDE4 Inhibitor TAK-648 in Type 2 Diabetes: Early Translational Approaches for Human Dose Prediction. [electronic resource]
Producer: 20180305Description: 185-193 p. digitalISSN:- 1752-8062
- Adult
- Aminopyridines -- adverse effects
- Animals
- Area Under Curve
- Benzamides -- adverse effects
- Cyclopropanes -- adverse effects
- Diabetes Mellitus, Type 2 -- blood
- Dose-Response Relationship, Drug
- Female
- Humans
- Male
- Mice
- Middle Aged
- Models, Biological
- Phosphodiesterase 4 Inhibitors -- adverse effects
- Translational Research, Biomedical
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Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
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