Metformin enhancing the antitumor efficacy of carboplatin against Ehrlich solid carcinoma grown in diabetic mice: Effect on IGF-1 and tumoral expression of IGF-1 receptors. [electronic resource]
Producer: 20170512Description: 72-86 p. digitalISSN:- 1878-1705
- Animals
- Antineoplastic Agents -- therapeutic use
- Apoptosis -- drug effects
- Carboplatin -- therapeutic use
- Carcinoma, Ehrlich Tumor -- complications
- Caspase 3 -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Diabetes Mellitus, Experimental -- complications
- Drug Synergism
- Female
- Humans
- Insulin-Like Growth Factor I -- metabolism
- Intercellular Signaling Peptides and Proteins -- metabolism
- Metformin -- therapeutic use
- Mice
- Mice, Inbred Strains
- Neovascularization, Pathologic -- complications
- Receptor, IGF Type 1 -- metabolism
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article
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