Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody-Drug Conjugates. [electronic resource]
Producer: 20170629Description: 116-123 p. digitalISSN:- 1538-8514
- Animals
- Antibodies, Monoclonal -- chemistry
- Antineoplastic Agents -- administration & dosage
- Cell Line, Tumor
- Cell Survival -- drug effects
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Stability
- Humans
- Immunoconjugates -- administration & dosage
- Maleimides -- chemistry
- Mice
- Molecular Structure
- Oligopeptides -- chemistry
- Polyethylene Glycols -- chemistry
- Survival Analysis
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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