Bromodomain protein Brd3 promotes Ifnb1 transcription via enhancing IRF3/p300 complex formation and recruitment to Ifnb1 promoter in macrophages. [electronic resource]
Producer: 20181010Description: 39986 p. digitalISSN:- 2045-2322
- Acetylation
- Animals
- CRISPR-Cas Systems -- genetics
- Cells, Cultured
- E1A-Associated p300 Protein -- metabolism
- Histones -- metabolism
- Interferon Regulatory Factor-3 -- metabolism
- Interferon-beta -- genetics
- Macrophages, Peritoneal -- cytology
- Mice
- Mice, Inbred C57BL
- Nuclear Proteins -- antagonists & inhibitors
- Promoter Regions, Genetic
- RAW 264.7 Cells
- RNA Interference
- RNA, Small Interfering -- metabolism
- Transcription Factors
- Transcriptional Activation
- Viruses -- pathogenicity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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