Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes. [electronic resource]
Producer: 20180220Description: 9922-9934 p. digitalISSN:- 1949-2553
- Animals
- Antibodies, Neutralizing -- pharmacology
- Autophagy -- drug effects
- Cell Line
- Chemical and Drug Induced Liver Injury -- immunology
- Cholestasis -- complications
- Cyclic S-Oxides -- pharmacology
- Hepatocytes -- drug effects
- Humans
- Interleukin-10 -- metabolism
- Interleukin-17 -- antagonists & inhibitors
- Liver -- drug effects
- Liver Cirrhosis, Experimental -- immunology
- Male
- Mice, Inbred BALB C
- Phosphorylation
- RNA Interference
- STAT3 Transcription Factor -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Th1 Cells -- drug effects
- Thioacetamide
- Transfection
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Publication Type: Journal Article
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