Synthesis, molecular docking and biological evaluation of 1-phenylsulphonyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as novel potential tubulin assembling inhibitors. [electronic resource]
Producer: 20170912Description: 112-118 p. digitalISSN:- 1747-0285
- A549 Cells
- Animals
- Benzimidazoles -- chemical synthesis
- Binding Sites
- Cell Cycle Checkpoints -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Colchicine -- chemistry
- Crystallography, X-Ray
- HeLa Cells
- Hep G2 Cells
- Humans
- MCF-7 Cells
- Mice
- Molecular Docking Simulation
- Protein Structure, Tertiary
- Quantitative Structure-Activity Relationship
- Tubulin -- chemistry
- Tubulin Modulators -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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