Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice. [electronic resource]
Producer: 20180810Description: 306-316 p. digitalISSN:- 1090-2139
- Alzheimer Disease -- genetics
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Cognition -- drug effects
- Disease Models, Animal
- Furans
- Heterocyclic Compounds, 4 or More Rings -- pharmacology
- Indenes
- Inflammasomes -- drug effects
- Mice
- Microglia -- drug effects
- NLR Family, Pyrin Domain-Containing 3 Protein -- metabolism
- Presenilin-1 -- genetics
- Sulfonamides
- Sulfones -- pharmacology
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Publication Type: Journal Article
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