A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers. [electronic resource]
Producer: 20180620Description: 39231 p. digitalISSN:- 2045-2322
- 3' Untranslated Regions
- Adult
- Aged
- Alleles
- Base Sequence
- CD8-Positive T-Lymphocytes -- cytology
- Cells, Cultured
- Cytotoxicity, Immunologic -- drug effects
- Disease Susceptibility
- Female
- Gene Expression Regulation, Neoplastic
- Gene Frequency
- Genotype
- HeLa Cells
- Humans
- Interferon-gamma -- metabolism
- Killer Cells, Natural -- cytology
- Male
- MicroRNAs -- chemistry
- Middle Aged
- NK Cell Lectin-Like Receptor Subfamily K -- antagonists & inhibitors
- Papillomaviridae -- isolation & purification
- Polymorphism, Single Nucleotide
- Sequence Alignment
- Transforming Growth Factor beta1 -- pharmacology
- Urogenital Neoplasms -- pathology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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