Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast. [electronic resource]
Producer: 20170711Description: 422-434 p. digitalISSN:- 1554-8937
- 14-alpha Demethylase Inhibitors -- chemistry
- Amino Acid Sequence
- Chagas Disease -- drug therapy
- Crystallography, X-Ray
- Directed Molecular Evolution
- Dose-Response Relationship, Drug
- Drug Discovery
- Gas Chromatography-Mass Spectrometry
- Molecular Docking Simulation
- Plasmodium falciparum -- drug effects
- Saccharomyces cerevisiae -- drug effects
- Spectrophotometry, Ultraviolet
- Sterol 14-Demethylase -- drug effects
- Trypanocidal Agents -- chemistry
- Trypanosoma cruzi -- drug effects
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Publication Type: Journal Article
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