Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation. [electronic resource]
Producer: 20170906Description: 349-364 p. digitalISSN:- 1558-8238
- Adolescent
- Adult
- Alleles
- Cell Line, Tumor
- Female
- Glycogen Synthase Kinase 3 beta -- genetics
- Humans
- Male
- Mechanistic Target of Rapamycin Complex 1
- Melanins -- biosynthesis
- Melanocytes -- metabolism
- Microphthalmia-Associated Transcription Factor -- genetics
- Middle Aged
- Multiprotein Complexes -- genetics
- Mutation
- Proto-Oncogene Proteins c-akt -- genetics
- Signal Transduction
- Skin Pigmentation
- TOR Serine-Threonine Kinases -- genetics
- Tuberous Sclerosis -- genetics
- Tuberous Sclerosis Complex 1 Protein
- Tuberous Sclerosis Complex 2 Protein
- Tumor Suppressor Proteins -- genetics
- beta Catenin -- genetics
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Publication Type: Journal Article
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