Pleural inhibition of the caspase-1/IL-1β pathway diminishes profibrotic lung toxicity of bleomycin. [electronic resource]
Producer: 20171204Description: 162 p. digitalISSN:- 1465-993X
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Bleomycin
- Caspase 1 -- metabolism
- Caspase Inhibitors -- pharmacology
- Cell Line
- Cytoprotection
- Disease Models, Animal
- Humans
- Idiopathic Pulmonary Fibrosis -- chemically induced
- Interleukin 1 Receptor Antagonist Protein -- pharmacology
- Interleukin-1beta -- antagonists & inhibitors
- Lung -- drug effects
- Mice, Inbred C57BL
- Nigericin -- pharmacology
- Pleura -- drug effects
- Signal Transduction -- drug effects
- Time Factors
- Transforming Growth Factor beta1 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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