Candesartan ameliorates arsenic-induced hypertensive vascular remodeling by regularizing angiotensin II and TGF-beta signaling in rats. [electronic resource]
Producer: 20170505Description: 29-41 p. digitalISSN:- 1879-3185
- Angiotensin II -- metabolism
- Angiotensin II Type 1 Receptor Blockers -- therapeutic use
- Animals
- Aorta, Thoracic -- pathology
- Arsenic Poisoning -- drug therapy
- Arsenites -- antagonists & inhibitors
- Benzimidazoles -- therapeutic use
- Biphenyl Compounds
- Blood Pressure -- drug effects
- Collagen -- metabolism
- Dose-Response Relationship, Drug
- Fibrosis -- pathology
- Male
- Rats
- Rats, Wistar
- Signal Transduction -- drug effects
- Smad Proteins -- metabolism
- Sodium Compounds -- antagonists & inhibitors
- Tetrazoles -- therapeutic use
- Transforming Growth Factor beta -- metabolism
- Vascular Remodeling -- drug effects
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Publication Type: Journal Article
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