SirT1 activator represses the transcription of TNF‑α in THP‑1 cells of a sepsis model via deacetylation of H4K16. [electronic resource]
Producer: 20170406Description: 5544-5550 p. digitalISSN:- 1791-3004
- Acetylation
- Cell Line
- Drug Resistance, Neoplasm -- genetics
- Enzyme Activation
- Gene Expression Regulation -- drug effects
- Histones -- metabolism
- Humans
- Macrophages -- drug effects
- Promoter Regions, Genetic
- Protein Binding
- RNA, Messenger -- genetics
- Resveratrol
- Sepsis -- drug therapy
- Sirtuin 1 -- metabolism
- Stilbenes -- pharmacology
- Transcription, Genetic -- drug effects
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article
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