Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition. [electronic resource]
Producer: 20190408Description: 1698-1701 p. digitalISSN:- 1097-6825
- Autoimmunity -- genetics
- CARD Signaling Adaptor Proteins -- genetics
- Calcium-Binding Proteins -- genetics
- Enterocolitis -- diagnosis
- Female
- Gene Expression Profiling
- Humans
- Infant
- Inflammasomes -- genetics
- Inflammation -- genetics
- Intercellular Signaling Peptides and Proteins -- pharmacology
- Interleukin-18 -- antagonists & inhibitors
- Macrophage Activation Syndrome -- diagnosis
- Mutation -- genetics
- Paramyxoviridae -- immunology
- Paramyxoviridae Infections -- diagnosis
- Polymorphism, Genetic
- Treatment Outcome
- Exome Sequencing
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Publication Type: Case Reports; Letter; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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