Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment. [electronic resource]
Producer: 20181211Description: 607-619 p. digitalISSN:- 0925-4439
- Alzheimer Disease -- drug therapy
- Amantadine -- analogs & derivatives
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Amyloid beta-Peptides -- antagonists & inhibitors
- Animals
- CHO Cells
- Cholinesterases -- metabolism
- Cricetulus
- Dimerization
- Enzyme Inhibitors -- chemistry
- HEK293 Cells
- Humans
- Molecular Targeted Therapy
- Receptor, Muscarinic M1 -- antagonists & inhibitors
- Receptors, Cholinergic -- metabolism
- Receptors, N-Methyl-D-Aspartate -- metabolism
- Tacrine -- analogs & derivatives
- Xenopus
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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