17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells. [electronic resource]
Producer: 20180905Description: 13426 p. digitalISSN:- 2041-1723
- Asthma -- genetics
- B-Lymphocytes -- metabolism
- Base Sequence
- Binding Sites -- genetics
- CCCTC-Binding Factor -- metabolism
- Cells, Cultured
- Chromosomes, Human, Pair 17 -- genetics
- Enhancer Elements, Genetic -- genetics
- Genetic Predisposition to Disease
- Humans
- Interleukin-2 -- biosynthesis
- Introns -- genetics
- Polymorphism, Single Nucleotide -- genetics
- Promoter Regions, Genetic -- genetics
- Protein Binding
- Risk Factors
- T-Lymphocytes -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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