Bisdemethoxycurcumin exerts pro-apoptotic effects in human pancreatic adenocarcinoma cells through mitochondrial dysfunction and a GRP78-dependent pathway. [electronic resource]
Producer: 20180205Description: 83641-83656 p. digitalISSN:- 1949-2553
- Adenocarcinoma -- drug therapy
- Antimetabolites, Antineoplastic -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Curcumin -- analogs & derivatives
- Deoxycytidine -- analogs & derivatives
- Diarylheptanoids
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm -- drug effects
- Endoplasmic Reticulum Chaperone BiP
- Eukaryotic Initiation Factor-2 -- metabolism
- Heat-Shock Proteins -- genetics
- Humans
- Mitochondria -- drug effects
- Pancreatic Neoplasms -- drug therapy
- Prohibitins
- Protein Deglycase DJ-1 -- metabolism
- Protein Interaction Maps
- RNA Interference
- Repressor Proteins -- metabolism
- Signal Transduction -- drug effects
- Transcription Factor CHOP -- metabolism
- Transfection
- Gemcitabine
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Publication Type: Journal Article
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