Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model. [electronic resource]
Producer: 20170825Description: 223-231 p. digitalISSN:- 1872-7980
- Administration, Metronomic
- Animals
- Antimetabolites, Antineoplastic -- administration & dosage
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colorectal Neoplasms -- enzymology
- Drug Combinations
- Humans
- Male
- Mice, Inbred BALB C
- Mice, Nude
- Oxonic Acid -- administration & dosage
- RNA Interference
- RNAi Therapeutics -- methods
- Tegafur -- administration & dosage
- Thymidylate Synthase -- genetics
- Time Factors
- Transfection
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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