The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton. [electronic resource]
Producer: 20170808Description: 57-64 p. digitalISSN:- 1872-7980
- Actin Cytoskeleton -- metabolism
- Adherens Junctions -- metabolism
- Animals
- Biomechanical Phenomena
- CDX2 Transcription Factor -- genetics
- Cell Movement
- Colonic Neoplasms -- genetics
- Fluorescent Antibody Technique
- Genes, APC
- Genetic Predisposition to Disease
- HT29 Cells
- Humans
- Mice, Transgenic
- Microscopy, Atomic Force
- Neoplasm Metastasis
- Phenotype
- Proto-Oncogene Proteins c-vav -- genetics
- RNA Interference
- Signal Transduction
- Transfection
- Tumor Suppressor Proteins -- genetics
- rho GTP-Binding Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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