Generation of an isogenic, gene-corrected iPSC line from a symptomatic 57-year-old female patient with frontotemporal dementia caused by a P301L mutation in the microtubule associated protein tau (MAPT) gene. [electronic resource]
Producer: 20180122Description: 556-559 p. digitalISSN:- 1876-7753
- Base Sequence
- CRISPR-Cas Systems -- genetics
- Cell Differentiation
- Cell Line
- Chromosomes, Human, Pair 17
- Dementia -- genetics
- Female
- Fibroblasts -- cytology
- Humans
- Induced Pluripotent Stem Cells -- cytology
- Karyotype
- Mesoderm -- cytology
- Microscopy, Fluorescence
- Middle Aged
- Polymorphism, Single Nucleotide
- Sequence Alignment
- Skin -- cytology
- tau Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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