HOXB4 knockdown reverses multidrug resistance of human myelogenous leukemia K562/ADM cells by downregulating P-gp, MRP1 and BCRP expression via PI3K/Akt signaling pathway. [electronic resource]
Producer: 20170417Description: 2529-2537 p. digitalISSN:- 1791-2423
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- biosynthesis
- ATP Binding Cassette Transporter, Subfamily G, Member 2 -- biosynthesis
- Antineoplastic Agents -- pharmacology
- Biological Transport -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cytarabine -- pharmacology
- Doxorubicin -- pharmacology
- Drug Resistance, Multiple -- genetics
- Drug Resistance, Neoplasm -- genetics
- Etoposide -- pharmacology
- Homeodomain Proteins -- genetics
- Humans
- Leukemia, Myeloid -- drug therapy
- Multidrug Resistance-Associated Proteins -- biosynthesis
- Neoplasm Proteins -- biosynthesis
- RNA Interference
- RNA, Small Interfering -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Transcription Factors -- genetics
- Vindesine -- pharmacology
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Publication Type: Journal Article
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