Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers. [electronic resource]
Producer: 20180904Description: 13047 p. digitalISSN:- 2041-1723
- Brain -- pathology
- Cell Proliferation
- Crystallography, X-Ray
- Endoplasmic Reticulum-Associated Degradation -- physiology
- HEK293 Cells
- Humans
- Intracellular Signaling Peptides and Proteins
- Mutation
- Oncogene Proteins, Fusion -- chemistry
- Peptides -- genetics
- Protein Binding
- Protein Domains -- physiology
- Protein Engineering
- Protein Interaction Maps
- Protein Multimerization
- Protein Structure, Quaternary
- Recombinant Proteins -- chemistry
- Valosin Containing Protein -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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