Impact of genetic variants of ATP binding cassette B1, AICAR transformylase/IMP cyclohydrolase, folyl-polyglutamatesynthetase, and methylenetetrahydrofolatereductase on methotrexate toxicity. [electronic resource]
Producer: 20180723Description: 318-325 p. digitalISSN:- 1885-1398
- ATP Binding Cassette Transporter, Subfamily B -- genetics
- Adult
- Age Factors
- Aged
- Alanine Transaminase -- blood
- Arthritis -- blood
- Biotransformation -- genetics
- Creatinine -- blood
- Female
- Hemoglobins -- analysis
- Humans
- Hydroxymethyl and Formyl Transferases -- genetics
- Immunosuppressive Agents -- adverse effects
- Leukocyte Count
- Liver -- drug effects
- Male
- Methotrexate -- adverse effects
- Methylenetetrahydrofolate Reductase (NADPH2) -- genetics
- Middle Aged
- Multienzyme Complexes -- genetics
- Nucleotide Deaminases -- genetics
- Peptide Synthases -- genetics
- Platelet Count
- Polymorphism, Single Nucleotide
- Sex Factors
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Publication Type: Comparative Study; Journal Article
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