Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy. [electronic resource]
Producer: 20171009Description: 872-881 p. digitalISSN:- 1476-5551
- Aged
- Aged, 80 and over
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Bone Marrow -- pathology
- Clonal Evolution -- genetics
- Epigenesis, Genetic -- drug effects
- Exome
- Female
- Genes, p53
- High-Throughput Nucleotide Sequencing
- Histone Deacetylase Inhibitors -- administration & dosage
- Humans
- Leukemia, Myeloid, Acute -- diagnosis
- Male
- Middle Aged
- Mutation
- Myelodysplastic Syndromes -- diagnosis
- Polymorphism, Single Nucleotide
- Remission Induction
- Treatment Outcome
- Tumor Burden
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Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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