Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells. [electronic resource]
Producer: 20170526Description: 1029-1035 p. digitalISSN:- 1548-7105
- CRISPR-Associated Proteins -- chemistry
- Cell Culture Techniques
- Clustered Regularly Interspaced Short Palindromic Repeats -- genetics
- Cytidine Deaminase -- chemistry
- Drug Resistance, Neoplasm -- genetics
- Fusion Proteins, bcr-abl -- genetics
- Gene Targeting
- Green Fluorescent Proteins -- chemistry
- HEK293 Cells
- Humans
- Imatinib Mesylate -- pharmacology
- K562 Cells
- Mutagenesis, Site-Directed
- Point Mutation
- RNA, Guide, CRISPR-Cas Systems
- Recombinant Fusion Proteins -- chemistry
- AICDA (Activation-Induced Cytidine Deaminase)
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Publication Type: Journal Article
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