6-(3,4-Dihydro-1H-isoquinoline-2-yl)-N-(6-methoxypyridine-2-yl) nicotinamide-26 (DIMN-26) decreases cell proliferation by induction of apoptosis and downregulation of androgen receptor signaling in human prostate cancer cells. [electronic resource]
Producer: 20170131Description: 196-207 p. digitalISSN:- 1872-7786
- Androgens -- pharmacology
- Apoptosis -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Nucleus -- drug effects
- Cell Proliferation -- drug effects
- Dihydrotestosterone -- pharmacology
- Down-Regulation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Isoquinolines -- chemistry
- Male
- Prostate-Specific Antigen -- genetics
- Prostatic Neoplasms -- drug therapy
- Protein Transport -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA, Messenger -- genetics
- Receptors, Androgen -- metabolism
- Signal Transduction -- drug effects
- Transcription, Genetic -- drug effects
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Publication Type: Journal Article
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