Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor. [electronic resource]
Producer: 20180910Description: 13084 p. digitalISSN:- 2041-1723
- Acetamides -- chemistry
- Antineoplastic Agents -- pharmacology
- Catalytic Domain
- Cell Line, Tumor
- Cell Movement
- Cell Survival
- Colonic Neoplasms -- drug therapy
- Crystallography, X-Ray
- Cysteine -- chemistry
- Drug Design
- Drug Resistance, Neoplasm
- Endoplasmic Reticulum -- metabolism
- Enzyme Inhibitors -- pharmacology
- Gene Silencing
- Glutathione Transferase -- antagonists & inhibitors
- HCT116 Cells
- High-Throughput Nucleotide Sequencing
- Humans
- Neoplasm Transplantation
- Oxidative Stress
- RNA, Small Interfering -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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