Synthesis, Pharmacological Profile and Docking Studies of New Sulfonamides Designed as Phosphodiesterase-4 Inhibitors. [electronic resource]
Producer: 20170614Description: e0162895 p. digitalISSN:- 1932-6203
- Animals
- Catalytic Domain
- Cyclic AMP -- analysis
- Cyclic Nucleotide Phosphodiesterases, Type 4 -- drug effects
- Eosinophil Peroxidase -- metabolism
- Guinea Pigs
- Humans
- Inflammation -- drug therapy
- Lung -- drug effects
- Male
- Mice
- Molecular Docking Simulation -- methods
- Muscle Contraction -- drug effects
- Muscle, Smooth -- chemistry
- Peroxidase -- metabolism
- Phosphodiesterase 4 Inhibitors -- chemical synthesis
- Protein Isoforms -- drug effects
- Respiratory Hypersensitivity -- drug therapy
- Sulfonamides -- chemical synthesis
- Trachea -- drug effects
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Publication Type: Journal Article
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