Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986). [electronic resource]
Producer: 20170606Description: 9457-9472 p. digitalISSN:- 1520-4804
- Administration, Oral
- Animals
- Benzoxazoles -- administration & dosage
- Cathepsin C -- antagonists & inhibitors
- Dogs
- Dose-Response Relationship, Drug
- Drug Discovery
- Humans
- Mice
- Molecular Structure
- Oxazepines -- administration & dosage
- Protease Inhibitors -- administration & dosage
- Rabbits
- Rats
- Structure-Activity Relationship
- U937 Cells
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Publication Type: Journal Article
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