Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation. [electronic resource]
Producer: 20180305Description: 73229-73241 p. digitalISSN:- 1949-2553
- Animals
- Capillary Permeability
- Caspase 1 -- metabolism
- Cathepsin B -- metabolism
- Cells, Cultured
- Diet, High-Fat
- Endothelial Cells -- drug effects
- Fatty Acids, Nonesterified
- Gene Deletion
- HMGB1 Protein -- metabolism
- Inflammasomes -- metabolism
- Lysosomes
- Male
- Mice
- Mice, Knockout
- Myocardium -- metabolism
- NLR Family, Pyrin Domain-Containing 3 Protein -- genetics
- Palmitates -- metabolism
- Permeability -- drug effects
- Tight Junctions -- metabolism
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Publication Type: Journal Article
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