Statin derivatives as therapeutic agents for castration-resistant prostate cancer. [electronic resource]
Producer: 20170724Description: 94-105 p. digitalISSN:- 1872-7980
- Androgen Antagonists -- pharmacology
- Antineoplastic Agents, Hormonal -- pharmacology
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cholesterol -- metabolism
- Docetaxel
- Dose-Response Relationship, Drug
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Male
- Neoplasm Invasiveness
- Prostatic Neoplasms, Castration-Resistant -- drug therapy
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptors, Androgen -- drug effects
- S Phase Cell Cycle Checkpoints -- drug effects
- Signal Transduction -- drug effects
- Simvastatin -- analogs & derivatives
- Taxoids -- pharmacology
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Publication Type: Journal Article
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