Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria. [electronic resource]
Producer: 20171211Description: 358ra128 p. digitalISSN:- 1946-6242
- Adenoviridae -- metabolism
- Angiopoietin-1 -- metabolism
- Animals
- Antimalarials -- pharmacology
- Artemisinins -- pharmacology
- Artesunate
- Blood-Brain Barrier -- pathology
- Child, Preschool
- Disease Models, Animal
- Disease Susceptibility
- Endothelial Cells -- drug effects
- Female
- Gene Deletion
- Humans
- Infant
- Kaplan-Meier Estimate
- Kinetics
- Malaria, Cerebral -- etiology
- Malaria, Falciparum -- metabolism
- Male
- Mice, Inbred C57BL
- Phenotype
- Plasmodium falciparum -- drug effects
- Receptor, TIE-2 -- metabolism
- Recombinant Proteins -- pharmacology
- Survival Analysis
- Treatment Outcome
- Uganda
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Publication Type: Journal Article; Randomized Controlled Trial
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