Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences. [electronic resource]
Producer: 20170410Description: 693-700 p. digitalISSN:- 1880-3989
- Animals
- Chemical and Drug Induced Liver Injury -- etiology
- Computational Biology
- Databases, Genetic
- Female
- Gene Expression Profiling -- methods
- Gene Expression Regulation, Developmental
- Liver -- drug effects
- Male
- Oligonucleotide Array Sequence Analysis
- PPAR alpha -- agonists
- RNA, Messenger -- genetics
- Rats, Sprague-Dawley
- Sex Factors
- Time Factors
- Triazoles -- toxicity
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Publication Type: Comparative Study; Letter
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