Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931. [electronic resource]
Producer: 20170612Description: L1000-L1014 p. digitalISSN:- 1522-1504
- Aldehyde-Lyases -- antagonists & inhibitors
- Animals
- Biological Transport -- drug effects
- Body Weight -- drug effects
- Cystic Fibrosis -- diagnostic imaging
- Cystic Fibrosis Transmembrane Conductance Regulator
- Cytokines -- metabolism
- Dendritic Cells -- drug effects
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Epithelial Cells -- drug effects
- Imidazoles -- pharmacology
- Lipopolysaccharides -- pharmacology
- Lung -- drug effects
- Lysophospholipids -- metabolism
- Mice, Inbred C57BL
- Mucin 5AC -- metabolism
- Mutation -- genetics
- Myeloid Cells -- drug effects
- N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
- Oximes -- pharmacology
- Pneumonia -- diagnostic imaging
- Salivary Glands -- drug effects
- Sphingosine -- analogs & derivatives
- X-Ray Microtomography
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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