Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant. [electronic resource]
Producer: 20180126Description: 11501-11506 p. digitalISSN:- 1091-6490
- Amino Acid Sequence
- Animals
- Antibodies, Blocking -- pharmacology
- CHO Cells
- Cattle
- Complementarity Determining Regions -- chemistry
- Cricetinae
- Cricetulus
- Drug Design
- HEK293 Cells
- Humans
- Immunosuppressive Agents -- pharmacology
- Kv1.3 Potassium Channel -- antagonists & inhibitors
- Lymphocyte Activation -- drug effects
- Rats
- Recombinant Fusion Proteins -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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