FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma. [electronic resource]
Producer: 20170717Description: 2192-2212 p. digitalISSN:- 1460-2075
- Aniline Compounds -- pharmacology
- Animals
- Benzamides
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Cell Movement
- Chromones -- pharmacology
- Cisplatin -- pharmacology
- F-Box Proteins -- genetics
- F-Box-WD Repeat-Containing Protein 7
- Glycogen Synthase Kinase 3 -- metabolism
- HEK293 Cells
- Humans
- Medulloblastoma -- drug therapy
- Mice, Nude
- Morpholines -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Pyrimidines -- pharmacology
- Pyrroles -- pharmacology
- SOX9 Transcription Factor -- genetics
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Ubiquitin-Protein Ligases -- genetics
- Ubiquitination
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Publication Type: Journal Article
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