Promising in vivo efficacy of the BET bromodomain inhibitor OTX015/MK-8628 in malignant pleural mesothelioma xenografts. [electronic resource]
Producer: 20170508Description: 197-207 p. digitalISSN:- 1097-0215
- Acetanilides -- administration & dosage
- Aged
- Animals
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cisplatin -- administration & dosage
- Deoxycytidine -- administration & dosage
- Down-Regulation
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Heterocyclic Compounds, 3-Ring -- administration & dosage
- Humans
- Lung Neoplasms -- drug therapy
- Male
- Mesothelioma -- drug therapy
- Mesothelioma, Malignant
- Mice
- Middle Aged
- Pemetrexed -- administration & dosage
- Proto-Oncogene Proteins c-myc -- metabolism
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Comparative Study; Journal Article
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